Dr Shikha’s Nutrihealth follows the concept which is derived from modern medical science and ayurveda
Prakriti analysis is an important fundamental theory of Ayurveda which involves understanding health and diseases known through Tridosha. This concept involves three bio energies Vata, Pitta, and Kapha and how human physiology is affected by it. The Prakriti analysis of a person provides a fair indication of his or her physiological weaknesses and strengths, general thought process, and susceptibility to various illnesses.
Each constitution type has specific physiological, physical and psychological characteristics which depend upon the predominance of each dosha in an individual.
Each Prakriti is found to have unique metabolic activities.
Prakriti is an individual’s genetic make-up that determines how the body responds to food.
It literally means ‘above’ or ‘on top of’ genetics. It refers to external modifications to the DNA, that turns the gene ‘on’ or ‘off’. These modifications do not change the DNA sequence, but instead, they affect how the cell read the genes.
The term epigenetics means the heritable changes in the gene expression (active versus inactive genes), that does not involve changes in the underlying DNA sequence; A change in phenotype without a change in genotype.
Factors that influence epigenetic changes are as follows:
- Disease State
- Lifestyle – Food Habits and Diet, Exercise, Smoking
- Environment – UV radiations, air pollutants
- Genetic Changes – Chromosome instability, mutation, double-strand break
- It may be possible to pass down epigenetic changes to the generation if the changes occur in sperm or egg cells. Most epigenetic changes that occur in sperm and egg cell get erased when the two combines to form a fertilized egg, in a process called “reprogramming”. It allows the cells of the fetus to start from scratch and make their own epigenetic changes.
- Some of the epigenetic changes in parents sperm and egg cell may avoid the reprogramming process and make it through the next generation.
Epigenetics and Nutrition
- Nutritional epigenetics explains the effects of nutrition on gene expression. Nutrients can reverse or change epigenetic phenomena, thereby modifying the expression of critical genes associated with physiologic and pathologic processes, including embryonic development, aging, and carcinogenesis.
- Nutritional epigenetics has also been viewed as an attractive tool to prevent pediatric developmental diseases and cancer as well as to delay aging-associated processes.
- Hence, food is also a conditioning environment that shapes the activity of the genome and the physiology of the body.
- The nutrients we extract from food enter metabolic pathways where they are manipulated, modified, and molded into molecules the body can use.
- Your mother’s diet during pregnancy and your diet as an infant can affect your epigenome in ways that stick with you into adulthood.
- Breastfeeding is one example as it can prevent various health issues in the later stages of life like Inflammatory Bowel Disease, Disorders of the Immune System, Obesity and Related Disorders and Cancer
Role of Foods in Epigenetics
- Vitamin D plays a major role in reversing aberrant epigenetic modifications. The active form of vitamin D, namely calcitriol, promotes cell cycle arrest, thus exerting an anti-tumor effect
- The intake of soy during childhood as well as consumption during adolescence has been associated with a decreased risk of breast cancer.
Diet and Epigenetics
Diet has also been shown to modify epigenetic tags in significant ways. The field of nutrigenomics explores how food and epigenetics work together to influence health and wellbeing. For example, a study found that a high fat, low carb diet could open up chromatin and improve mental ability via HDAC inhibitors.
Ultimately, an epigenetic diet may guide people toward the optimal food regimen as scientific studies reveal the underlying mechanisms and impact that different foods have on the epigenome and health.
- Dietary compounds such as sulforaphane (SFN) found in cruciferous vegetables and epigallocatechin-3-gallate (EGCG) in green tea exhibit the ability to affect various epigenetic mechanisms.
- The regular consumption of EGCG, a green tea polyphenol, or green tea itself may also decrease the risk of Colorectal, oesophageal, breast, hepatocellular, ovarian, pancreatic and prostate cancer development in adults.